The IRF5 polymorphism in type 1 diabetes
نویسندگان
چکیده
منابع مشابه
Significant Associations of the rs3104413 Single-nucleotide Polymorphism in the HLA Region with Type 1 Diabetes
Background and Aims: In this study, the effect of rs310441 polymorphism in the human leukocyte antigen (HLA) region on the development of susceptibility or resistance to Type 1 diabetes (T1D) among the people with T1D compared to healthy subjects has been investigated. Materials and Methods: This research, which is based on the examination of 130 cases with T1D and 98 controls, has been carrie...
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Background: Type 1 Diabetes (T1D) is a chronic and progressive autoimmune disorder. Cytokines play a critical role in the pathogenesis of T1D. Objective: IFN-¹ polymorphism was investigated in T1D and compared with normal controls. Methods: Thirty patients suffering from T1D and 40 normal controls were studied simultaneously using PCR technique. IFN- ¹ gene was evaluated at position 5’UTR...
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Introduction: Type 2 diabetes is a common multifactorial disease. Studies have shown that the NLRP3 gene plays an important role in insulin resistance. The aim of this study was to investigate the association of rs4612666 polymorphisms of NLRp3 gene with type 2 diabetes in the population of East Azarbaijan province. Methods: In this case-control study, blood samples from 110 patients and 110 h...
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Type I diabetes mellitus is a common chronic disease in adolescents. According to statistics, 12,243 diabetic Muslims fast in thirteen Islamic countries, 43% of whom have type I diabetes. This longitudinal study was conducted on volunteer adolescents with type I diabetes aged 13-18 years for 15 days using the census method. Three days before Ramadan and during the last three days of the study p...
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AK1 catalyzes the reversible reaction ATP+AMP 2ADP thus contributing to the regulation of relative concentration of these important nucleotides. Intracellular ATP is a storage of energy for cellular processes, moreover extracellular ATP together with ADP, AMP and adenosine are critical signalling molecule for sending messages to nearby cells acting on P1 and P2 receptors. AK1 shows a genetic ...
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ژورنال
عنوان ژورنال: Journal of Medical Genetics
سال: 2007
ISSN: 1468-6244
DOI: 10.1136/jmg.2007.050971